Biological Safety Cabinet Levels

The purifier axiom class ii type c1 is the first biological safety cabinet that can be used in a recirculating type a mode for standard microbiological work or can be connected to an exhaust system to function in type b mode for handling hazardous chemical vapors or radionuclides.

Biological safety cabinet levels.

It is commonly found in clinical and research laboratories working with infectious agents in risk groups 2 3 and 4 if positive pressure suits are used or with tissue culture. Every microbiology laboratory regardless of biosafety level follows standard microbiological practices. The axiom is an r d 100 awards for innovation finalist. A class ii biological safety cabinet bsc is a ventilated cabinet which provides personnel product and environmental protection.

Information about the biosafety level requirements for handling sar cov 2 covid 19 coronavirus can be found here. Class ii biological safety cabinets like class i safety cabinets class ii cabinets have a stream of inward air moving into the cabinet. The bsl 4 laboratory should contain a class iii biological safety cabinet but may use a class i or ii bsc in combination with a positive pressure air supplied full body suit. Class i cabinets are safe for use with agents requiring biosafety level 1 2 or 3 containment.

All class i biological safety cabinets are suitable for work with microbiological agents assigned to biosafety levels 1 2 and 3. Usually bsl 4 laboratories are in separate buildings or a totally isolated zone with dedicated supply and exhaust ventilation. Class ii a class ii cabinet is defined as a ventilated cabinet for personnel product and environmental protection for microbiological work or sterile pharmacy compounding. The biosafety levels range from bsl 1 to bsl 4.

Biological safety levels bsl are a series of protections relegated to autoclave related activities that take place in particular biological labs they are individual safeguards designed to protect laboratory personnel as well as the surrounding environment and. Biosafety level 4 bsl 4 is the highest level of biosafety precautions and is appropriate for work with agents that could easily be aerosol transmitted within the laboratory and cause severe to fatal disease in humans for which there are no available vaccines or treatments. This is known as the inflow and it prevents the aerosol generated during. Procedures with a high likelihood of generating aerosols or droplets should be done using either a certified class ii biological safety cabinet bsc or additional precautions to provide a barrier between the specimen and personnel.

You will learn about each level on the following screens. Each biosafety level builds on the controls of the level before it.